Limited value for urinary 5-HIAA excretion as prognostic marker in gastrointestinal neuroendocrine tumours
نویسندگان
چکیده
منابع مشابه
Limited value for urinary 5-HIAA excretion as prognostic marker in gastrointestinal neuroendocrine tumours.
OBJECTIVE To determine if urinary 5-hydroxyindoleacetic acid (5-HIAA) excretion is of prognostic value for overall survival (OS) in patients with a gastrointestinal neuroendocrine tumour (NET) and to compare the prognostic value with patient characteristics, ENETS/WHO grading, ENETS TNM staging and biomarkers. DESIGN AND METHODS Data was collected from patients with a gastrointestinal NET or ...
متن کاملA single fasting plasma 5-HIAA value correlates with 24-hour urinary 5-HIAA values and other biomarkers in midgut neuroendocrine tumors (NETs).
OBJECTIVES 5-Hydroxyindoleacetic acid (5-HIAA) is used for the evaluation of neuroendocrine tumors (NETs) but currently requires a 24-hour urine collection. METHODS We developed a gas chromatography mass spectroscopy-based plasma 5-HIAA assay. We compared 24-hour urine 5-HIAA values against plasma 5-HIAA values in 115 mixed-variety patients with NETs and in a subset of 72 patients with only s...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 2016
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje-16-0392